Overview
This formulation combines two complementary growth hormone-axis peptides acting via distinct but synergistic receptor pathways: Ipamorelin (a selective ghrelin receptor agonist) and CJC-1295 (a GHRH analogue with Drug Affinity Complex technology for extended half-life).
Ipamorelin
- Selective GH Release: Stimulates GH release without significantly affecting cortisol, ACTH, or prolactin – a cleaner research model for GH pulsatility studies than earlier-generation GHRPs.
- GHS-R1a Agonism: Acts on the primary ghrelin receptor subtype for GH secretagogue activity.
- Molecular Weight: 711.86 g/mol | CAS: 170851-70-4
CJC-1295
- GHRH Analogue: Modified GHRH(1-29) with DAC technology enabling covalent albumin binding, extending bioactive half-life from minutes to days in animal models.
- Pituitary Research: Studied for sustained stimulation of somatotroph cells and downstream GH/IGF-1 axis effects.
- Molecular Weight: 3647.28 g/mol | CAS: 863288-34-0
Combination Rationale
Ipamorelin triggers a sharp GH pulse via the GHRP pathway; CJC-1295 amplifies and prolongs GH release via the GHRH pathway. Combined, they create a synergistic somatotroph stimulation studied in body composition, metabolic, and anti-ageing research models.
For in vitro laboratory research use only. Not for human or animal administration.
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