Retatrutide 10mg
Retatrutide - a novel GIP/GLP-1/glucagon triple receptor agonist. Among the most advanced incretin-axis research compounds, studied for simultaneous multi-receptor modulation of energy homeostasis, adiposity, and glucose metabolism.
89,99 €
≥99% HPLC purityThird-party tested · Discreet packaging · Ships from the EU
Specifications
- CAS
- 2381089-83-2
- MW
- 4731.3 g/mol
- SKU
- RETA-10MG
- Storage
- −20 °C, dry, protected from light
Usage Notes
This compound is intended exclusively for in vitro research. Refer to peer-reviewed literature for dosing protocols and experimental methodologies.
Disclaimer: Not for human or animal consumption. Not approved by EMA or FDA.
Retatrutide 10mg
Research profile
Overview
Retatrutide (LY3437943) is a synthetic peptide engineered to simultaneously agonise three key metabolic receptors: glucose-dependent insulinotropic polypeptide receptor (GIPR), glucagon-like peptide-1 receptor (GLP-1R), and glucagon receptor (GCGR). This triple receptor engagement represents one of the most advanced incretin research pharmacology profiles currently studied.
Key Research Areas
-
Triple Incretin Receptor Agonism
Simultaneous engagement of GIP-R, GLP-1R, and GCGR modulates complementary and synergistic pathways in energy homeostasis – a more comprehensive metabolic signalling profile than single or dual agonists. -
Adipose Tissue Research
Phase 2 clinical data published in the NEJM (2023) demonstrated substantial body weight reduction, making it a central compound in obesity mechanism research. -
Glucose Homeostasis
GLP-1 and GIP components contribute to glucose-dependent insulin secretion; the glucagon component adds hepatic glucose output modulation. -
Hepatic Research
GCGR agonism studied for its role in NAFLD/NASH models through hepatic lipid oxidation and gluconeogenesis modulation. -
Thermogenesis Models
Glucagon component investigated for brown adipose tissue activation and increased basal metabolic rate.
Specifications
| CAS | 2381089-83-2 |
|---|---|
| Molecular Weight | 4731.3 g/mol |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilised powder, 10 mg per vial (3ml) |
For in vitro laboratory research use only. Not for human or animal administration.
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