Healing & Regeneration

TB-500

54,99 €

CAS 77591-33-4
SKU TB500-10MG
For in vitro research use only. Not for human or animal consumption.

Overview

TB-500 corresponds to the actin-binding domain (residues 17-23) of Thymosin Beta-4 (Tb4), a naturally occurring protein found in virtually all nucleated cells. It is among the most studied regenerative peptides, with a substantial body of preclinical research across multiple tissue types.

Key Research Areas

  • Actin Polymerisation: Sequesters G-actin, facilitating cytoskeletal remodelling critical for cellular migration during tissue repair.
  • Anti-inflammatory Activity: Downregulates pro-inflammatory cytokines (IL-1b, TNF-a) in multiple injury models.
  • Angiogenesis: Promotes new capillary formation, studied in cardiac and musculoskeletal injury models.
  • Cardiac Research: Investigated in myocardial infarction models for cardiac progenitor cell activation and cardiomyocyte survival.
  • Satellite Cell Activation: Research suggests activation of skeletal muscle stem cells, relevant to muscle regeneration models.

Specifications

  • Molecular Formula: C212H350N56O78S
  • Molecular Weight: 4963.44 g/mol
  • CAS: 77591-33-4
  • Purity: ≥99% (HPLC verified)
  • Form: Lyophilised powder, 10 mg per vial

For in vitro laboratory research use only. Not for human or animal administration.