TB-500 10mg
TB-500 is a synthetic analogue of Thymosin Beta-4, a ubiquitous 43-amino acid actin-sequestering peptide. Studied for cellular migration, angiogenesis, anti-inflammatory activity, and muscle satellite cell activation in injury and regeneration models.
54,99 €
≥99% HPLC purityThird-party tested · Discreet packaging · Ships from the EU
Specifications
- CAS
- 77591-33-4
- SKU
- TB500-10MG
Usage Notes
This compound is intended exclusively for in vitro research. Refer to peer-reviewed literature for dosing protocols and experimental methodologies.
Disclaimer: Not for human or animal consumption. Not approved by EMA or FDA.
TB-500 10mg
Research profile
Overview
TB-500 corresponds to the actin-binding domain (residues 17-23) of Thymosin Beta-4 (Tb4), a naturally occurring protein found in virtually all nucleated cells. It is among the most studied regenerative peptides, with a substantial body of preclinical research across multiple tissue types.
Key Research Areas
-
Actin Polymerisation
Sequesters G-actin, facilitating cytoskeletal remodelling critical for cellular migration during tissue repair. -
Anti-inflammatory Activity
Downregulates pro-inflammatory cytokines (IL-1b, TNF-a) in multiple injury models. -
Angiogenesis
Promotes new capillary formation, studied in cardiac and musculoskeletal injury models. -
Cardiac Research
Investigated in myocardial infarction models for cardiac progenitor cell activation and cardiomyocyte survival. -
Satellite Cell Activation
Research suggests activation of skeletal muscle stem cells, relevant to muscle regeneration models.
Specifications
| Molecular Formula | C212H350N56O78S |
|---|---|
| Molecular Weight | 4963.44 g/mol |
| CAS | 77591-33-4 |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilised powder, 10 mg per vial |
For in vitro laboratory research use only. Not for human or animal administration.
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