SLU-PP-332 250mcg – 60 Capsules
SLU-PP-332 - a synthetic pan-agonist of estrogen-related receptors ERRa/b/g. Studied as an exercise mimetic through activation of mitochondrial biogenesis pathways, AMPK signalling, and oxidative metabolic reprogramming in skeletal muscle and cardiac models.
79,99 €
≥99% HPLC purityThird-party tested · Discreet packaging · Ships from the EU
Specifications
- CAS
- 303760-60-3
- MW
- 290.3 g/mol
- SKU
- SLUPP332-60CAP
Usage Notes
This compound is intended exclusively for in vitro research. Refer to peer-reviewed literature for dosing protocols and experimental methodologies.
Disclaimer: Not for human or animal consumption. Not approved by EMA or FDA.
SLU-PP-332 250mcg - 60 Capsules
Research profile
Overview
SLU-PP-332 is a potent synthetic agonist for the estrogen-related receptor (ERR) family, specifically ERRa, ERRb, and ERRg. These nuclear receptors are master regulators of mitochondrial biogenesis and oxidative metabolism. Their activation has been studied as a molecular mechanism underlying endurance exercise adaptation.
Key Research Areas
-
Exercise Mimetic Research
ERRa and ERRg control gene expression programs activated by endurance training. Published in Nature Communications (2023), SLU-PP-332 was shown to upregulate OXPHOS genes and increase running endurance in animal models without physical training. -
Mitochondrial Biogenesis
Acts upstream of PGC-1a to drive mitochondrial number and function – studied in ageing, metabolic disease, and heart failure models. -
AMPK Pathway Activation
Demonstrated activation of AMPK leading to increased fatty acid oxidation and decreased lipid accumulation in muscle cells. -
Cardiac Research
ERRa and ERRg are highly expressed in cardiomyocytes; studied in heart failure models for effects on cardiac energy metabolism. -
Metabolic Syndrome Models
Increased fatty acid oxidation and reduced adipogenesis make it a subject in obesity mechanism research.
Specifications
| CAS | 303760-60-3 |
|---|---|
| Purity | ≥99% (HPLC verified) |
| Form | Capsules (microcrystalline cellulose carrier) |
| Quantity | 60 capsules x 250 mcg |
For in vitro laboratory research use only. Not for human or animal administration.
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