Overview
BPC-157 is a pentadecapeptide sequence studied across multiple preclinical models for its cytoprotective and tissue-repairing properties. It is derived from a protective protein found in gastric juice and has been the subject of extensive in vitro and in vivo research over the past three decades.
Key Research Areas
- Angiogenesis: Shown to upregulate VEGF expression and promote new vessel formation in tissue repair models.
- Nitric Oxide System: Interacts with NO-synthase pathways, modulating nitric oxide availability in injured microenvironments.
- Fibroblast Activation: Accelerates fibroblast migration and proliferation in wound healing assays, contributing to collagen matrix deposition.
- Tendon-to-Bone Healing: Studied in musculoskeletal models for reattachment of severed tendons and ligaments.
- GI Mucosal Research: Explored in intestinal permeability and inflammatory bowel models given its gastric origin.
Specifications
- Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
- Molecular Formula: C62H98N16O22
- Molecular Weight: 1419.55 g/mol
- CAS: 137525-51-0
- Purity: ≥99% (HPLC verified)
- Form: Lyophilised powder, 10 mg per vial
For in vitro laboratory research use only. Not for human or animal administration.
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